Early Intervention Cuts Risk of Lifelong Osteoporosis
Delay in XXY diagnosis results in significantly increased risk of osteoporosis and fractures later in life: optimal care with supplementation during puberty allows to reach peak bone mass and quality/quantity of bone in adulthood.

For more information click here:
Prevelence of Vertebral Fractures in Patients with Klinefelter
American Society of Andrology and European Academy of Andrology, June 2020